As a pediatrician with a special interest in infectious disease epidemiology and public health, Dr Quique Bassat combines his clinical activities with biomedical research in those diseases that most affect the poor and vulnerable. Dr Bassat has worked in Manhiça, Mozambique as a pediatrician and clinical researcher, participating in various clinical trials related to malaria prevention and treatment, such as RTS,S malaria candidate vaccine clinical trials (infant and older children studies). He also led the Manhiça component of phase III multicenter antimalarial drug studies that were important for the clinical development of new antimalarial drugs (dihydroartemisinin-piperaquine; dispersible artemether-lumefantrine). Dr Bassat is particularly interested in the study of the burden, trends, and characterization of malaria in children admitted to hospitals, and the overlapping symptomatology between malaria and other common infectious diseases.
While his work initially focused on Plasmodium falciparum malaria and children, his research interests currently include the study of P. vivax. In recent years, in addition to the ongoing work in Mozambique, he has coordinated the implementation of various P. vivax related studies in countries such as Brazil, India, and Papua New Guinea, aiming to describe in greater depth the epidemiology and clinical manifestations related to this species. Such work has included the first fully-characterized large series of P. vivax severe cases collected from two very distinct countries (Brazilian Amazon and Rajasthan, India) following an identical protocol, and the first series of P. vivax associated deaths fully studied through complete autopsy.
Since 2013, Dr Bassat has been based in Manhiça, Mozambique as part of the Mozambique Alliance toward the Elimination of Malaria Initiative. His main research project is related to the validation of minimally invasive autopsy tools for the post-mortem investigation of causes of death in the developing world.